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Volume 8, Issue 1, Year 2022 (Jan-Feb-Mar)
Tuberculosis is one of the first most common causes of death in the world alongside HIV/AIDS, causing considerable mortality globally. Tuberculosis is also accompanied by hematological alterations although the alteration related to the disease is not well determined yet and showed variation in different studies. This study aimed at evaluating hematological profiles in pulmonary tuberculosis patients in Metema hospital and Gondar referral Hospital, North West Ethiopia. A case-control study design was conducted from January to July 2018. A total of 88 blood samples (44 from cases and 44 from control groups) were collected. The collected blood samples were tested using a Hematology analyzer (Sysmex) for hematological profiles. The mean+standard deviation of hemoglobin, hematocrit, and red blood cell count of the cases were significantly lower than the control groups (P< 0.05). However, platelet and total white blood cell counts; and erythrocyte sedimentation rate were significantly increased as compared with control groups (p<0.05). Body mass index had significant positive associations with red blood cell count, hemoglobin, and hematocrit (P < 0.05). Pulmonary Tuberculosis patients in this study showed hematological profile abnormalities; where the red blood cell count, hematocrit and hemoglobin were significantly reduced. However, the total white blood cell count, thrombocyte, and erythrocyte sedimentation rate of tuberculosis patients were significantly elevated than control groups. The factors associated with hematological profile alterations require a due attention to prevent further complications and further studies should be conducted.
Severe acute respiratory syndrome coronavirus 2 pandemic has swamped the entire world. It can target any organ of the body and symptoms can vary from none or mild to even dreadful life-threatening respiratory distress or multisystem organ failure. A conglomeration of ocular symptoms and signs keep outpouring from various parts of the world ranging from conjunctivitis, uveitis to sight-threatening retinal vascular occlusions and calamitous rhino-orbital mucormycosis. Ocular manifestations can be attributed to either direct invasion by the virus or immune-mediated insult of the ocular tissues or triggering of coagulation cascade inducing prothrombotic state This article aims to delineate ocular manifestation of COVID-19 briefly which will be instrumental in early diagnosis, management, and timely vision restoration.
Basal cell carcinoma is the most common skin malignancy constituting 90% of eyelid tumors. Although it rarely metastasizes, it needs to be addressed with timely diagnosis and prompt treatment to avoid disfigurement of the tissues it invades. We report a case of 72 years old male with basal cell carcinoma of the lateral canthus. The patient was planned for excision of the lesion. Despite the excision of a large tumor involving the lateral canthus of the left eye (3*3 cm) and a large portion adjoining the upper and lower eyelids (1.5 cm approximately), we were able to restore the eyelid contour at the lateral canthus. There have been many proposed treatment modalities for basal cell carcinoma however excision biopsy remains the gold standard. This article outlines the etio-pathogenesis, clinical features, and various treatment modalities in the management of basal cell carcinoma.
