PLWHIV in Northeast Nigeria were investigated for the prevalence of infection and to identify risk factors associated with HPgV infection, given the potential impact of HPgV on HIV disease progression. In Northeast Nigeria, we conducted a cross-sectional study of 249 PLWHIV. We used bivariate and multivariate logistic regression models to assess the association between HPgV infection and sociodemographic characteristics, risk behaviors, and healthcare access. 23.3% of the study population had HPgV infection. In the multivariate analysis, inhaled drug use was associated with HPgV infection. In Northeast Nigeria, there is a concerning prevalence of HPgV infection among PLWHIV. A potential transmission route beyond traditional routes is suggested by the identification of inhaled drug use as a risk factor. To address this significant public health concern, targeted interventions and harm reduction strategies are necessary.
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